Yes, but the result differs. On light melange, with dyed or blended fibres, the ground has a speckled texture that shows through thin or transparent prints. Prints with strong coverage, such as plastisol or DTF, hide the ground well.
On melange containing polyester, for example 60/40 cotton-polyester grey, there is a risk of disperse dye migration under heat. The printed colour can look different from the ground, especially with water-based ink. Ask for a test on the melange lot itself, not on a different grey.
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